Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PHLPP1LOW QUALITY PROTEIN: PH domain leucine-rich repeat-containing protein phosphatase 1. (1707 aa)    
Predicted Functional Partners:
PHLPP2
PH domain leucine-rich repeat-containing protein phosphatase 2 isoform X1.
  
 
0.982
AKT1
AKT serine/threonine kinase 1.
    
 0.975
AKT3
AKT serine/threonine kinase 3.
    
 0.957
AKT2
RAC-beta serine/threonine-protein kinase.
    
 0.957
WDR48
LOW QUALITY PROTEIN: WD repeat-containing protein 48.
   
 
 0.924
USP1
Ubiquitin specific peptidase 1.
    
 
 0.923
SUGT1
Protein SGT1 homolog isoform X1.
    
 
 0.895
FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5.
    
 
 0.881
SNX27
Sorting nexin-27 isoform X1.
    
 
 0.867
SLC9A3R2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform X1.
    
 
 0.830
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.