Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTF2Metal-response element-binding transcription factor 2 isoform X1. (592 aa)    
Predicted Functional Partners:
JARID2
Protein Jumonji isoform X1.
    
 0.983
SUZ12
Polycomb protein SUZ12.
   
 0.983
EZH2
Histone-lysine N-methyltransferase EZH2 isoform X1.
   
 0.974
EZH1
[histone H3]-lysine27 N-trimethyltransferase EZH1.
   
 0.955
EED
Embryonic ectoderm development.
   
 0.952
RBBP4
Histone-binding protein RBBP4 isoform X1.
   
 0.839
SKIDA1
SKI/DACH domain-containing protein 1.
    
 
 0.838
ENSPCIP00000001693
annotation not available
    
 0.833
RBBP7
Histone-binding protein RBBP7.
   
 0.810
ENSPCIP00000032456
annotation not available
   
 0.810
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (26%) [HD]