Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PKD2Polycystin-2 isoform X1. (984 aa)    
Predicted Functional Partners:
PKD1
LOW QUALITY PROTEIN: polycystin-1.
   
 0.992
TRPC1
Transient receptor potential cation channel subfamily C member 1.
   
 
 0.812
IBSP
Integrin binding sialoprotein.
   
 
 0.783
EXOC2
Exocyst complex component 2 isoform X1.
     
  0.747
EXOC5
Exocyst complex component 5.
     
 0.743
EXOC4
Exocyst complex component 4 isoform X1.
     
 0.701
RHO
Rhodopsin.
     
 0.700
IFT20
Intraflagellar transport protein 20 homolog isoform X1.
   
  
 0.685
PKD1L2
LOW QUALITY PROTEIN: polycystic kidney disease protein 1-like 2.
    
 
 0.682
PKDREJ
Polycystic kidney disease and receptor for egg jelly-related protein.
   
 0.680
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.