Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NPHS2Podocin. (424 aa)    
Predicted Functional Partners:
CD2AP
CD2 associated protein.
   
 
 0.914
NPHS1
Nephrin isoform X1.
   
 0.879
TRPC6
Transient receptor potential cation channel subfamily C member 6.
    
 
 0.842
KIRREL1
Kin of IRRE-like protein 1 isoform X1.
    
 0.775
SYNPO
LOW QUALITY PROTEIN: synaptopodin.
   
 
 0.759
PLCE1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1.
      
 0.732
ENSPCIP00000038320
Inverted formin-2-like isoform X1.
    
 0.702
WT1
Wilms tumor protein isoform X1.
   
 0.684
SH3KBP1
SH3 domain-containing kinase-binding protein 1 isoform X1.
   
 
 0.677
SLC12A1
Solute carrier family 12 (sodium/potassium/chloride transporter), member 1.
   
 
 0.667
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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