Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAX4Paired box 4. (325 aa)    
Predicted Functional Partners:
INS
Insulin.
   
 0.830
TIMM22
Mitochondrial import inner membrane translocase subunit TIM22.
    
 0.739
SST
Somatostatin.
      
 0.738
SUZ12
Polycomb protein SUZ12.
    
 0.707
FOXA1
Forkhead box protein A1, hepatocyte nuclear factor 3-alpha.
   
 0.691
FOXA2
Forkhead box protein A2, hepatocyte nuclear factor 3-beta.
   
 0.683
POU1F1
Pituitary-specific positive transcription factor 1 isoform X1.
   
 0.671
NKX2-2
Homeobox protein Nkx-2.2.
   
 
 0.645
MYB
Transcriptional activator Myb isoform X1.
     
 0.628
TIMM10
Mitochondrial import inner membrane translocase subunit TIM10.
   
 0.621
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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