Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAPK4Mitogen-activated protein kinase 4/6. (580 aa)    
Predicted Functional Partners:
MAPK6
Mitogen-activated protein kinase 4/6.
   
 
  0.982
MAPKAPK5
Mitogen-activated protein kinase-activated protein kinase 5.
    
 0.961
XPO1
Exportin-1.
    
 0.865
FOS
Proto-oncogene protein c-fos.
    
 0.776
FOSB
Protein fosB isoform X1.
    
 0.771
FOSL1
Fos-related antigen 1.
    
 0.771
JUN
Transcription factor AP-1.
    
 0.760
JUND
Transcription factor jun-D.
    
 0.754
PAK2
Serine/threonine-protein kinase PAK 2 isoform X1.
    
 0.706
ENSPCIP00000027419
annotation not available
    
 0.706
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.