Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EML5Echinoderm microtubule-associated protein-like 5 isoform X1. (1977 aa)    
Predicted Functional Partners:
MIS12
Kinetochore-associated protein MIS12.
     
 0.510
IFT140
LOW QUALITY PROTEIN: intraflagellar transport protein 140 homolog.
   
 0.505
ZNF500
KRAB and SCAN domains-containing zinc finger protein.
    
 0.491
ENSPCIP00000012987
annotation not available
      
 0.490
SLC6A7
Solute carrier family 6 (neurotransmitter transporter, L-proline) member 7.
      
 0.490
NEK9
NIMA (never in mitosis gene a)-related kinase 9.
   
  0.484
ENSPCIP00000018195
E3 SUMO-protein ligase RanBP2-like.
   
 0.452
CDK17
Cyclin-dependent kinase 17 isoform X1.
   
 0.439
PES1
Pescadillo homolog.
   
 0.430
ARHGAP1
Rho GTPase-activating protein 1 isoform X1.
   
  
 0.428
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (14%) [HD]