Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HOMER1Homer scaffold protein 1. (385 aa)    
Predicted Functional Partners:
HOMER3
Homer protein homolog 3.
    
0.995
GRM1
LOW QUALITY PROTEIN: metabotropic glutamate receptor 1.
    
 0.987
SHANK1
SH3 and multiple ankyrin repeat domains protein 1 isoform X1.
    
 0.965
HOMER2
Homer protein homolog 2 isoform X1.
  
 
 
0.934
SHANK3
SH3 and multiple ankyrin repeat domains 3.
    
 0.931
C1orf116
Specifically androgen-regulated gene protein-like isoform X1.
    
   0.911
ENSPCIP00000032817
annotation not available
    
 0.880
GRM5
Metabotropic glutamate receptor 5 isoform X1.
    
 0.880
SYNGAP1
LOW QUALITY PROTEIN: ras/Rap GTPase-activating protein SynGAP.
    
 
 0.859
DBN1
Drebrin isoform X1.
    
 
 0.829
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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