STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSPO4R-spondin 4. (224 aa)    
Predicted Functional Partners:
LGR4
Leucine-rich repeat-containing G protein-coupled receptor 4.
   
 0.962
RNF43
LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF43.
   
 0.940
LGR6
Leucine-rich repeat-containing G-protein coupled receptor 6 isoform X1.
    
 0.930
ZNRF3
E3 ubiquitin-protein ligase ZNRF3 isoform X1.
   
 0.926
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
   
 0.563
BMP5
Bone morphogenetic protein 5 isoform X1.
   
 0.514
RXFP2
Relaxin family peptide receptor 2.
   
 0.493
ENSPCIP00000039227
Relaxin family peptide receptor 2.
   
 0.493
RXFP1
Relaxin family peptide receptor 1.
   
 0.493
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase isoform X1.
     
 0.427
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.