Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRPM5Transient receptor potential cation channel subfamily M member 5. (1162 aa)    
Predicted Functional Partners:
CALHM1
Calcium homeostasis modulator protein 1.
      
 0.839
TAS1R3
Taste receptor type 1 member 3.
      
 0.822
DCLK1
Serine/threonine-protein kinase DCLK1 isoform X1.
   
  
 0.783
PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1.
   
 
 0.762
POU2F3
LOW QUALITY PROTEIN: POU domain, class 2, transcription factor 3.
    
 
 0.757
IL25
Interleukin 17E.
      
 0.755
GNAT3
Guanine nucleotide-binding protein G(t) subunit alpha-3 isoform X1.
      
 0.748
PKD2L1
Polycystin 2 like 1, transient receptor potential cation channel.
      
 0.740
ASCL3
Achaete-scute homolog 3 isoform X1.
      
 0.735
PKD1L2
LOW QUALITY PROTEIN: polycystic kidney disease protein 1-like 2.
      
 0.726
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (20%) [HD]