STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCM2Cerebral cavernous malformations 2 protein isoform X1. (450 aa)    
Predicted Functional Partners:
PDCD10
Programmed cell death protein 10.
    
 
 0.963
KRIT1
Krev interaction trapped protein 1 isoform X1.
    
 
 0.963
MAP3K3
Mitogen-activated protein kinase kinase kinase 3 isoform X1.
    
 0.962
ITGB1BP1
Integrin beta-1-binding protein 1 isoform X1.
    
 
 0.814
EFCAB2
EF-hand calcium-binding domain-containing protein 2 isoform X1.
    
 0.602
FLNA
Filamin-A isoform X1.
    
 0.571
VCL
Vinculin isoform X1.
    
 0.564
SH3BGR
SH3 domain-binding glutamic acid-rich protein.
   
  
 0.561
SMURF1
E3 ubiquitin-protein ligase SMURF1 isoform X1.
    
 0.551
MUC13
Mucin-13.
   
  
 0.491
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.