Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VCAM1LOW QUALITY PROTEIN: vascular cell adhesion protein 1. (719 aa)    
Predicted Functional Partners:
ITGA4
Integrin alpha 4.
    
 0.986
ITGB1
Integrin beta-1 isoform X1.
    
 0.986
NFKB1
Nuclear factor kappa B subunit 1.
    
 0.975
ITGA9
Integrin alpha 9.
    
 0.969
ITGB7
LOW QUALITY PROTEIN: integrin beta-7.
    
 0.956
RELA
Transcription factor p65 isoform X1.
    
 0.947
ENSPCIP00000014896
Cytochrome b-245 heavy chain.
   
 
 0.938
NCF1
Neutrophil cytosol factor 1 isoform X1.
    
 0.922
EZR
LOW QUALITY PROTEIN: ezrin.
    
 0.922
MSN
Moesin.
    
 0.922
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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