Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GAB2Growth factor receptor bound protein 2-associated protein 2. (662 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-binding protein 2.
    
 0.995
ENSPCIP00000013537
Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.
    
 0.984
PTPN11
Tyrosine-protein phosphatase non-receptor type 11 isoform X1.
    
 0.984
PIK3R1
Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.
   
 0.962
PIK3R2
Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.
   
 0.958
PIK3R3
Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.
   
 0.958
EGFR
Epidermal growth factor receptor isoform X1.
   
 0.951
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2.
   
 0.947
LYN
Tyrosine-protein kinase Lyn isoform X1.
   
 0.947
KIT
Mast/stem cell growth factor receptor Kit isoform X1.
    
 0.941
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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