STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNKSTankyrase-1. (1392 aa)    
Predicted Functional Partners:
AXIN1
Axin-1 isoform X1.
    
 0.973
RNF146
E3 ubiquitin-protein ligase RNF146 isoform X1.
    
 0.951
TERF1
Telomeric repeat-binding factor 1 isoform X1.
    
 0.928
AXIN2
LOW QUALITY PROTEIN: axin-2.
    
 0.919
MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1 isoform X1.
    
 
 0.747
TINF2
TERF1-interacting nuclear factor 2 isoform X1.
    
 0.714
GMDS
GDP-mannose 4,6 dehydratase isoform X1.
    
 
 0.701
HIF1AN
LOW QUALITY PROTEIN: hypoxia-inducible factor 1-alpha inhibitor.
    
 
 0.677
BABAM1
BRISC and BRCA1-A complex member 1 isoform X1.
    
 0.663
ENSPCIP00000005621
annotation not available
   
 0.616
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.