STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY2Protein sprouty homolog 2. (316 aa)    
Predicted Functional Partners:
CBLB
E3 ubiquitin-protein ligase CBL-B isoform X1.
    
 0.754
CBL
E3 ubiquitin-protein ligase CBL isoform X1.
    
 0.754
CBLC
E3 ubiquitin-protein ligase CBL-C isoform X1.
    
 0.735
GRB2
Growth factor receptor-binding protein 2.
    
 0.575
FGF8
Fibroblast growth factor 8.
   
  
 0.532
GRAP2
GRB2-related adapter protein 2 isoform X1.
    
 0.532
GRAP
GRB2-related adapter protein.
    
 0.532
SPRY1
Protein sprouty homolog 1.
  
0.497
HBEGF
Proheparin-binding EGF-like growth factor.
   
 
 0.445
PPP2CB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform.
    
  0.431
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.