STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRG2LOW QUALITY PROTEIN: pro-neuregulin-2, membrane-bound isoform. (625 aa)    
Predicted Functional Partners:
EGFR
Epidermal growth factor receptor isoform X1.
    
 0.986
ERBB2
LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-2.
    
 0.984
ERBB3
Receptor tyrosine-protein kinase erbB-3 isoform X1.
    
 0.981
ERBB4
LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-4.
    
 0.981
NRG4
Pro-neuregulin-4, membrane-bound isoform isoform X1.
    
 0.968
NRG1
Pro-neuregulin-1, membrane-bound isoform isoform X1.
     
0.962
NRG3
Pro-neuregulin-3, membrane-bound isoform.
     
0.926
ENSPCIP00000044298
annotation not available
    
 0.820
EGF
Pro-epidermal growth factor isoform X1.
    
0.643
SLIT2
Slit homolog 2 protein isoform X1.
   
 0.521
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.