STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PWWP2APWWP domain containing 2A. (752 aa)    
Predicted Functional Partners:
WRN
Werner syndrome ATP-dependent helicase.
   
 0.985
ATR
LOW QUALITY PROTEIN: serine/threonine-protein kinase ATR.
   
 0.935
NBN
Nibrin isoform X1.
    
 0.934
NBR1
Next to BRCA1 gene 1 protein isoform X1.
     
 0.918
MRE11
LOW QUALITY PROTEIN: double-strand break repair protein MRE11.
   
 0.913
RAD50
DNA repair protein RAD50.
   
 0.889
TP53BP1
Tumor suppressor p53-binding protein 1 isoform X1.
    
 0.856
CHEK2
Serine/threonine-protein kinase Chk2 isoform X1.
    
 0.848
SLF1
SMC5-SMC6 complex localization factor protein 1 isoform X1.
   
 0.826
XRCC6
X-ray repair cross-complementing protein 6 isoform X1.
    
 0.818
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.