STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKPleckstrin. (350 aa)    
Predicted Functional Partners:
FHDC1
LOW QUALITY PROTEIN: FH2 domain-containing protein 1.
      
 0.677
GRID2IP
Delphilin isoform X1.
   
 
 0.654
FMN2
LOW QUALITY PROTEIN: formin-2.
      
 0.542
ENSPCIP00000018163
annotation not available
      
 0.505
DIAPH1
Protein diaphanous homolog 1 isoform X1.
      
 0.496
RGS18
Regulator of G-protein signaling 18.
   
  
 0.476
BTK
Bruton agammaglobulinemia tyrosine kinase.
   
  
 0.470
APPL1
DCC-interacting protein 13 alpha.
   
  
 0.434
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
  
 0.434
FERMT3
Fermitin family homolog 3.
   
  
 0.409
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.