STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIC1Hypermethylated in cancer 1 protein isoform X1. (752 aa)    
Predicted Functional Partners:
SIRT1
LOW QUALITY PROTEIN: NAD-dependent protein deacetylase sirtuin-1.
    
 
 0.599
HMMR
Hyaluronan mediated motility receptor.
   
 0.505
ENSPCIP00000040169
annotation not available
    
 0.504
CD200
OX-2 membrane glycoprotein-like isoform X1.
      
 0.489
CTBP1
C-terminal-binding protein 1 isoform X1.
    
 
 0.443
CTBP2
LOW QUALITY PROTEIN: C-terminal-binding protein 2.
    
 
 0.443
MNT
LOW QUALITY PROTEIN: max-binding protein MNT.
   
 
 0.433
SKA3
Spindle and kinetochore-associated protein 3 isoform X1.
      
 0.430
UBE2I
SUMO-conjugating enzyme UBC9 isoform X1.
    
 0.408
MGMT
Methylated-DNA--protein-cysteine methyltransferase isoform X1.
      
 0.408
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.