STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMURF1E3 ubiquitin-protein ligase SMURF1 isoform X1. (730 aa)    
Predicted Functional Partners:
SMAD7
Mothers against decapentaplegic homolog 7.
    
 0.999
SMAD6
Mothers against decapentaplegic homolog 6.
    
 0.994
PTCH1
Protein patched homolog 1 isoform X1.
    
 0.976
TGFBR1
TGF-beta receptor type-1.
    
 0.975
SMURF2
E3 ubiquitin-protein ligase SMURF2 isoform X1.
  
0.975
SMAD1
Mothers against decapentaplegic homolog 1.
    
 0.973
TGFBR2
TGF-beta receptor type-2.
    
 0.970
SMAD5
Mothers against decapentaplegic homolog 5.
    
 0.894
SMAD4
Mothers against decapentaplegic homolog 4.
   
 0.822
UBC
LOW QUALITY PROTEIN: polyubiquitin-C.
    
 0.815
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.