PDGFRB protein (Phascolarctos cinereus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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Coexpression

Experiments

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[Homology]

Score

PDGFRB

Platelet-derived growth factor receptor beta isoform X1. (1095 aa)

Predicted Functional Partners:

PDGFB

0.999

PLCG1

0.996

PIK3R1

0.995

PLCG2

0.988

GRB2

0.988

ENSPCIP00000013537

0.985

PTPN11

0.985

PDGFRA

0.984

PDGFC

0.972

PIK3R2

0.972

Your Current Organism:

Phascolarctos cinereus

NCBI taxonomy Id: 38626
Other names: P. cinereus, koala

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPCIP00000013537	GRB2	ENSPCIP00000013537	ENSPCIP00000049493	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	Growth factor receptor-binding protein 2.	0.997
ENSPCIP00000013537	PDGFRA	ENSPCIP00000013537	ENSPCIP00000054280	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	Platelet-derived growth factor receptor alpha.	0.966
ENSPCIP00000013537	PDGFRB	ENSPCIP00000013537	ENSPCIP00000026410	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	Platelet-derived growth factor receptor beta isoform X1.	0.985
ENSPCIP00000013537	PIK3R1	ENSPCIP00000013537	ENSPCIP00000010629	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.978
ENSPCIP00000013537	PIK3R2	ENSPCIP00000013537	ENSPCIP00000037290	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	0.958
ENSPCIP00000013537	PLCG1	ENSPCIP00000013537	ENSPCIP00000042342	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1.	0.495
ENSPCIP00000013537	PLCG2	ENSPCIP00000013537	ENSPCIP00000020081	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2.	0.550
ENSPCIP00000013537	PTPN11	ENSPCIP00000013537	ENSPCIP00000025080	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	Tyrosine-protein phosphatase non-receptor type 11 isoform X1.	0.901
GRB2	ENSPCIP00000013537	ENSPCIP00000049493	ENSPCIP00000013537	Growth factor receptor-binding protein 2.	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	0.997
GRB2	PDGFB	ENSPCIP00000049493	ENSPCIP00000050524	Growth factor receptor-binding protein 2.	Platelet-derived growth factor subunit B isoform X1.	0.409
GRB2	PDGFRA	ENSPCIP00000049493	ENSPCIP00000054280	Growth factor receptor-binding protein 2.	Platelet-derived growth factor receptor alpha.	0.970
GRB2	PDGFRB	ENSPCIP00000049493	ENSPCIP00000026410	Growth factor receptor-binding protein 2.	Platelet-derived growth factor receptor beta isoform X1.	0.988
GRB2	PIK3R1	ENSPCIP00000049493	ENSPCIP00000010629	Growth factor receptor-binding protein 2.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.976
GRB2	PIK3R2	ENSPCIP00000049493	ENSPCIP00000037290	Growth factor receptor-binding protein 2.	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	0.818
GRB2	PLCG1	ENSPCIP00000049493	ENSPCIP00000042342	Growth factor receptor-binding protein 2.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1.	0.960
GRB2	PLCG2	ENSPCIP00000049493	ENSPCIP00000020081	Growth factor receptor-binding protein 2.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2.	0.887
GRB2	PTPN11	ENSPCIP00000049493	ENSPCIP00000025080	Growth factor receptor-binding protein 2.	Tyrosine-protein phosphatase non-receptor type 11 isoform X1.	0.997
PDGFB	GRB2	ENSPCIP00000050524	ENSPCIP00000049493	Platelet-derived growth factor subunit B isoform X1.	Growth factor receptor-binding protein 2.	0.409
PDGFB	PDGFC	ENSPCIP00000050524	ENSPCIP00000032539	Platelet-derived growth factor subunit B isoform X1.	Platelet derived growth factor C/D.	0.983
PDGFB	PDGFRA	ENSPCIP00000050524	ENSPCIP00000054280	Platelet-derived growth factor subunit B isoform X1.	Platelet-derived growth factor receptor alpha.	0.995