STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIAS4E3 SUMO-protein ligase PIAS4. (494 aa)    
Predicted Functional Partners:
SUMO1
Small ubiquitin-related modifier 1.
    
 0.981
SUMO2
Small ubiquitin-related modifier 2.
    
 0.960
SUMO3
Small ubiquitin-related modifier 3.
    
 0.960
TP53
Cellular tumor antigen p53.
    
 0.934
UBE2I
SUMO-conjugating enzyme UBC9 isoform X1.
    
 0.913
PRKCZ
Protein kinase C zeta type isoform X1.
 
  
 0.911
STAT1
Signal transducer and activator of transcription 1-alpha/beta.
   
 0.863
STAT3
Signal transducer and activator of transcription 3 isoform X1.
   
 0.837
ENSPCIP00000013837
annotation not available
    
 0.825
STAT4
Signal transducer and activator of transcription 4 isoform X1.
   
 0.825
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.