STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOP1DNA topoisomerase 1 isoform X1. (767 aa)    
Predicted Functional Partners:
TDP1
Tyrosyl-DNA phosphodiesterase 1 isoform X1.
    
 
 0.861
TOP2A
DNA topoisomerase 2-alpha.
   
 
 0.845
TOP2B
DNA topoisomerase 2-beta isoform X1.
   
 
 0.773
WRN
Werner syndrome ATP-dependent helicase.
   
 
 0.767
BLM
Bloom syndrome protein.
   
 
 0.750
RNASEH2A
Ribonuclease H2 subunit A.
    
 
 0.701
FEN1
Flap endonuclease 1.
   
 
 0.654
POLE
LOW QUALITY PROTEIN: DNA polymerase epsilon catalytic subunit A.
    
 
 0.649
ENSPCIP00000046034
annotation not available
    
 
 0.627
KCTD2
LOW QUALITY PROTEIN: BTB/POZ domain-containing protein KCTD2.
    
 0.603
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.