STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SREBF2Sterol regulatory element-binding transcription factor 2. (1159 aa)    
Predicted Functional Partners:
SCAP
Sterol regulatory element-binding protein cleavage-activating protein.
   
 0.980
KPNB1
Importin subunit beta-1.
    
 0.947
NPC1
Niemann-Pick C1 protein isoform X1.
   
 0.872
NPC1L1
Niemann-Pick C1-like protein 1.
   
 0.834
MBTPS2
Membrane-bound transcription factor site-2 protease isoform X1.
    
 0.806
SREBF1
Sterol regulatory element binding transcription factor 1.
  
 
0.759
MBTPS1
Membrane-bound transcription factor site-1 protease.
     
 0.738
HMGCR
3-hydroxy-3-methylglutaryl-Coenzyme A reductase.
     
 0.699
TP53
Cellular tumor antigen p53.
   
 
 0.683
HMGCS1
Hydroxymethylglutaryl-CoA synthase, cytoplasmic.
   
 
 0.633
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.