STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOCS4Suppressor of cytokine signaling 4. (436 aa)    
Predicted Functional Partners:
SOCS3
Suppressor of cytokine signaling 3.
     
0.949
JAK2
LOW QUALITY PROTEIN: tyrosine-protein kinase JAK2.
    
 0.945
SOCS2
Suppressor of cytokine signaling 2 isoform X1.
     
0.940
INSR
Insulin receptor isoform X1.
    
 0.922
IRS1
Insulin receptor substrate 1.
    
 0.915
IRS2
Insulin receptor substrate 2 isoform X1.
    
 0.915
CUL5
Cullin 5.
   
 0.837
TYK2
Non-receptor tyrosine-protein kinase TYK2.
    
 0.807
JAK1
Tyrosine-protein kinase JAK1 isoform X1.
    
 0.807
JAK3
Tyrosine-protein kinase JAK3.
    
 0.807
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.