STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APTXAprataxin isoform X1. (351 aa)    
Predicted Functional Partners:
XRCC1
X-ray repair cross complementing 1.
    
 
 0.746
WRN
Werner syndrome ATP-dependent helicase.
   
  
 0.731
TDP1
Tyrosyl-DNA phosphodiesterase 1 isoform X1.
    
 
 0.620
LIG4
DNA ligase 4.
   
 
 0.606
LIG3
DNA ligase 3 isoform X1.
   
 
 0.564
APLF
Aprataxin and PNK-like factor isoform X1.
      
 0.552
XRCC6
X-ray repair cross-complementing protein 6 isoform X1.
      
 0.552
PARP2
poly(ADP-ribose) polymerase 2.
   
 
 0.546
OGG1
N-glycosylase/DNA lyase.
    
 
 0.526
LIG1
DNA ligase 1.
   
 
 0.514
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.