STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIX3Homeobox protein SIX3 isoform X1. (330 aa)    
Predicted Functional Partners:
VAX2
Homeobox protein ventral anterior.
   
 
 0.594
NODAL
Nodal homolog.
      
 0.509
EYA2
EYA transcriptional coactivator and phosphatase 2.
   
 
 0.506
EYA1
Eyes absent homolog 1 isoform X1.
   
 
 0.506
EYA3
Eyes absent homolog 3 isoform X1.
   
 
 0.506
EYA4
LOW QUALITY PROTEIN: eyes absent homolog 4.
   
 
 0.506
RIN1
Ras and Rab interactor 1 isoform X1.
      
 0.456
PFDN2
Prefoldin subunit 2.
      
 0.452
LHX5
LIM/homeobox protein Lhx5.
    
 
 0.440
EN2
Engrailed homeobox 2.
      
 0.432
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.