STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPCIP000000434135-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase. (508 aa)    
Predicted Functional Partners:
HSD3B7
3 beta-hydroxysteroid dehydrogenase type 7 isoform X1.
   
 0.962
AKR1D1
3-oxo-5-beta-steroid 4-dehydrogenase.
   
 
 0.906
LSS
Lanosterol synthase isoform X1.
   
 0.842
MSMO1
Methylsterol monooxygenase 1.
   
 0.761
FAXDC2
Fatty acid hydroxylase domain-containing protein 2 isoform X1.
   
 0.761
CH25H
Cholesterol 25-hydroxylase.
   
 0.761
FDFT1
Farnesyl-diphosphate farnesyltransferase.
  
 
 0.754
ERG28
Probable ergosterol biosynthetic protein 28.
   
 
 0.743
HSD17B7
17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase.
   
 
 0.740
SQLE
Squalene monooxygenase isoform X1.
   
 0.738
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.