STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FASTumor necrosis factor receptor superfamily member 6. (394 aa)    
Predicted Functional Partners:
FADD
FAS-associated death domain protein.
   
 0.999
FASLG
Tumor necrosis factor ligand superfamily member 6.
    
 0.998
DAXX
Death domain-associated protein 6 isoform X1.
    
 0.988
TNFRSF1A
Tumor necrosis factor receptor superfamily member 1A.
    
0.972
FAF1
FAS-associated factor 1 isoform X1.
    
 0.966
CASP8
Caspase 8.
   
 0.900
CASP10
Caspase-10 isoform X1.
   
 0.900
CFLAR
CASP8 and FADD-like apoptosis regulator isoform X1.
   
 0.853
RIPK1
Receptor-interacting serine/threonine-protein kinase 1 isoform X1.
   
 0.816
ENSPCIP00000045439
annotation not available
    
 
 0.815
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.