node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDJ90880.1 | SDK36167.1 | SAMN05216282_101252 | SAMN05216282_105108 | L-threonine ammonia-lyase. | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | 0.908 |
SDJ90880.1 | SDK84118.1 | SAMN05216282_101252 | SAMN05216282_1153 | L-threonine ammonia-lyase. | Tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase. | 0.824 |
SDJ90880.1 | SDL15406.1 | SAMN05216282_101252 | SAMN05216282_1364 | L-threonine ammonia-lyase. | Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family. | 0.774 |
SDJ90880.1 | ilvC | SAMN05216282_101252 | SAMN05216282_11535 | L-threonine ammonia-lyase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.848 |
SDJ90880.1 | ilvD | SAMN05216282_101252 | SAMN05216282_11538 | L-threonine ammonia-lyase. | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. | 0.919 |
SDJ90880.1 | ilvN | SAMN05216282_101252 | SAMN05216282_11536 | L-threonine ammonia-lyase. | Acetolactate synthase, small subunit. | 0.990 |
SDJ90880.1 | leuA | SAMN05216282_101252 | SAMN05216282_11923 | L-threonine ammonia-lyase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.501 |
SDJ90880.1 | leuB | SAMN05216282_101252 | SAMN05216282_11520 | L-threonine ammonia-lyase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.824 |
SDK35839.1 | SDK36167.1 | SAMN05216282_10598 | SAMN05216282_105108 | Kynurenine formamidase. | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | 0.750 |
SDK36167.1 | SDJ90880.1 | SAMN05216282_105108 | SAMN05216282_101252 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | L-threonine ammonia-lyase. | 0.908 |
SDK36167.1 | SDK35839.1 | SAMN05216282_105108 | SAMN05216282_10598 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | Kynurenine formamidase. | 0.750 |
SDK36167.1 | SDK84118.1 | SAMN05216282_105108 | SAMN05216282_1153 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | Tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase. | 0.734 |
SDK36167.1 | SDK87371.1 | SAMN05216282_105108 | SAMN05216282_1169 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | Phosphotransacetylase. | 0.797 |
SDK36167.1 | SDL15406.1 | SAMN05216282_105108 | SAMN05216282_1364 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family. | 0.688 |
SDK36167.1 | ilvC | SAMN05216282_105108 | SAMN05216282_11535 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.962 |
SDK36167.1 | ilvD | SAMN05216282_105108 | SAMN05216282_11538 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. | 0.811 |
SDK36167.1 | ilvN | SAMN05216282_105108 | SAMN05216282_11536 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | Acetolactate synthase, small subunit. | 0.989 |
SDK36167.1 | leuA | SAMN05216282_105108 | SAMN05216282_11923 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.813 |
SDK36167.1 | leuB | SAMN05216282_105108 | SAMN05216282_11520 | Acetolactate synthase large subunit; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.734 |
SDK84118.1 | SDJ90880.1 | SAMN05216282_1153 | SAMN05216282_101252 | Tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase. | L-threonine ammonia-lyase. | 0.824 |