node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDK03885.1 | SDK60483.1 | SAMN05216282_102209 | SAMN05216282_108125 | Glutamate or tyrosine decarboxylase. | Aspartate aminotransferase. | 0.797 |
SDK03885.1 | hutH | SAMN05216282_102209 | SAMN05216282_10986 | Glutamate or tyrosine decarboxylase. | Histidine ammonia-lyase. | 0.794 |
SDK60483.1 | SDK03885.1 | SAMN05216282_108125 | SAMN05216282_102209 | Aspartate aminotransferase. | Glutamate or tyrosine decarboxylase. | 0.797 |
SDK60483.1 | hisC | SAMN05216282_108125 | SAMN05216282_11276 | Aspartate aminotransferase. | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.866 |
SDK60483.1 | hutH | SAMN05216282_108125 | SAMN05216282_10986 | Aspartate aminotransferase. | Histidine ammonia-lyase. | 0.795 |
SDK60483.1 | pat | SAMN05216282_108125 | SAMN05216282_105187 | Aspartate aminotransferase. | Histidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.882 |
SDK64491.1 | hutH | SAMN05216282_10985 | SAMN05216282_10986 | Transcriptional regulator, IclR family. | Histidine ammonia-lyase. | 0.759 |
SDK64491.1 | hutI | SAMN05216282_10985 | SAMN05216282_10992 | Transcriptional regulator, IclR family. | Imidazolonepropionase. | 0.503 |
aroC | hisC | SAMN05216282_103244 | SAMN05216282_11276 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.801 |
aroC | hutH | SAMN05216282_103244 | SAMN05216282_10986 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Histidine ammonia-lyase. | 0.804 |
aroC | pat | SAMN05216282_103244 | SAMN05216282_105187 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Histidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.694 |
aroC | trpE | SAMN05216282_103244 | SAMN05216282_103213 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.976 |
hisC | SDK60483.1 | SAMN05216282_11276 | SAMN05216282_108125 | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Aspartate aminotransferase. | 0.866 |
hisC | aroC | SAMN05216282_11276 | SAMN05216282_103244 | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.801 |
hisC | hisD | SAMN05216282_11276 | SAMN05216282_102235 | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.999 |
hisC | hutH | SAMN05216282_11276 | SAMN05216282_10986 | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Histidine ammonia-lyase. | 0.805 |
hisC | pat | SAMN05216282_11276 | SAMN05216282_105187 | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Histidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.883 |
hisC | trpE | SAMN05216282_11276 | SAMN05216282_103213 | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.595 |
hisD | hisC | SAMN05216282_102235 | SAMN05216282_11276 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.999 |
hisD | hutH | SAMN05216282_102235 | SAMN05216282_10986 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | Histidine ammonia-lyase. | 0.908 |