STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDK98904.1Pyrimidine reductase, riboflavin biosynthesis. (260 aa)    
Predicted Functional Partners:
ribA
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
  
 0.983
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
 0.826
SDK98937.1
Cysteine desulfuration protein SufE.
       0.810
SDK98961.1
Thiosulfate/3-mercaptopyruvate sulfurtransferase.
       0.809
SDK47051.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
  
 
0.803
SDK47024.1
Riboflavin synthase alpha chain.
  
 
 0.797
SDK05176.1
Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family.
  
  
 0.793
zapE
Cell division protein ZapE.
       0.630
SDK72551.1
Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
      
 0.596
SDK02063.1
Hypothetical protein.
    
   0.474
Your Current Organism:
Cryobacterium psychrotolerans
NCBI taxonomy Id: 386301
Other names: C. psychrotolerans, CGMCC 1.5382, Cryobacterium psychrotolerans Zhang et al. 2007, Cryobacterium sp. 0549, JCM 13925, strain 0549
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