STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDL05832.1Hypothetical protein. (194 aa)    
Predicted Functional Partners:
SDK37607.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.956
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.920
SDK35269.1
DNA polymerase-1.
  
 0.920
SDK46144.1
DNA polymerase-3 subunit delta'.
   
 0.783
SDJ86145.1
Exonuclease SbcC.
   
 0.751
sbcD
Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
 0.675
SDL01046.1
Metallo-beta-lactamase family protein.
   
 0.594
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
  0.578
SDJ84230.1
Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily.
  
 
 0.559
SDK54186.1
Exodeoxyribonuclease-3.
  
 
 0.559
Your Current Organism:
Cryobacterium psychrotolerans
NCBI taxonomy Id: 386301
Other names: C. psychrotolerans, CGMCC 1.5382, Cryobacterium psychrotolerans Zhang et al. 2007, Cryobacterium sp. 0549, JCM 13925, strain 0549
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.