node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK61437.1 | ABK62654.1 | NT01CX_1626 | NT01CX_0807 | Nicotinate phosphoribosyltransferase, putative; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | MutT/nudix family protein, putative; Identified by match to protein family HMM PF00293. | 0.918 |
ABK61437.1 | birA | NT01CX_1626 | NT01CX_0898 | Nicotinate phosphoribosyltransferase, putative; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | birA bifunctional protein, putative; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.551 |
ABK61437.1 | cinA | NT01CX_1626 | NT01CX_0942 | Nicotinate phosphoribosyltransferase, putative; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA; Identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; Belongs to the CinA family. | 0.966 |
ABK61437.1 | guaA | NT01CX_1626 | NT01CX_0459 | Nicotinate phosphoribosyltransferase, putative; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.414 |
ABK61437.1 | nadD | NT01CX_1626 | NT01CX_0075 | Nicotinate phosphoribosyltransferase, putative; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.952 |
ABK61437.1 | nadE | NT01CX_1626 | NT01CX_0103 | Nicotinate phosphoribosyltransferase, putative; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.803 |
ABK62365.1 | birA | NT01CX_0261 | NT01CX_0898 | Uroporphyrinogen III synthase/methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469. | birA bifunctional protein, putative; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.590 |
ABK62365.1 | guaA | NT01CX_0261 | NT01CX_0459 | Uroporphyrinogen III synthase/methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.449 |
ABK62365.1 | nadD | NT01CX_0261 | NT01CX_0075 | Uroporphyrinogen III synthase/methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.444 |
ABK62365.1 | nadE | NT01CX_0261 | NT01CX_0103 | Uroporphyrinogen III synthase/methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469. | Glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.777 |
ABK62365.1 | purD | NT01CX_0261 | NT01CX_2418 | Uroporphyrinogen III synthase/methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469. | Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF01071; match to protein family HMM PF02769; match to protein family HMM PF02842; match to protein family HMM PF02843; match to protein family HMM PF02844; match to protein family HMM TIGR00877; match to protein family HMM TIGR01857; Belongs to the GARS family. | 0.531 |
ABK62654.1 | ABK61437.1 | NT01CX_0807 | NT01CX_1626 | MutT/nudix family protein, putative; Identified by match to protein family HMM PF00293. | Nicotinate phosphoribosyltransferase, putative; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.918 |
ABK62654.1 | cinA | NT01CX_0807 | NT01CX_0942 | MutT/nudix family protein, putative; Identified by match to protein family HMM PF00293. | Competence/damage-inducible protein CinA; Identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; Belongs to the CinA family. | 0.915 |
ABK62654.1 | cobB-2 | NT01CX_0807 | NT01CX_0771 | MutT/nudix family protein, putative; Identified by match to protein family HMM PF00293. | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.917 |
ABK62654.1 | nadD | NT01CX_0807 | NT01CX_0075 | MutT/nudix family protein, putative; Identified by match to protein family HMM PF00293. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.905 |
ABK62654.1 | nadE | NT01CX_0807 | NT01CX_0103 | MutT/nudix family protein, putative; Identified by match to protein family HMM PF00293. | Glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.911 |
ABK62654.1 | nadK | NT01CX_0807 | NT01CX_1985 | MutT/nudix family protein, putative; Identified by match to protein family HMM PF00293. | ATP-NAD kinase, putative; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.900 |
birA | ABK61437.1 | NT01CX_0898 | NT01CX_1626 | birA bifunctional protein, putative; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Nicotinate phosphoribosyltransferase, putative; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.551 |
birA | ABK62365.1 | NT01CX_0898 | NT01CX_0261 | birA bifunctional protein, putative; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Uroporphyrinogen III synthase/methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469. | 0.590 |
birA | cinA | NT01CX_0898 | NT01CX_0942 | birA bifunctional protein, putative; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Competence/damage-inducible protein CinA; Identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; Belongs to the CinA family. | 0.476 |