STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK61143.1RNA polymerase sigma-F factor; Identified by match to protein family HMM PF04539; match to protein family HMM PF04542; match to protein family HMM PF04545; Belongs to the sigma-70 factor family. (251 aa)    
Predicted Functional Partners:
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.985
ABK61991.1
Anti-sigma F factor antagonist; Identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; Belongs to the anti-sigma-factor antagonist family.
 
  
 0.934
ABK60787.1
Stage V sporulation protein AC; Identified by match to protein family HMM PF03862.
 
     0.902
ABK60880.1
Stage V sporulation protein AE; Identified by match to protein family HMM PF03862.
 
     0.883
ABK62164.1
Stage V sporulation AD, SpoVAD; Identified by match to protein family HMM PF07451.
 
     0.882
ABK61150.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
     0.746
ABK61035.1
Stage II sporulation protein E; Identified by match to protein family HMM PF07228.
  
   
 0.719
spoIIID
Stage III sporulation protein D.
  
   
 0.714
ABK60602.1
Stage IV sporulation protein B, SpoIVB; Identified by match to protein family HMM PF00595; match to protein family HMM PF05580.
  
   
 0.708
ABK61161.1
Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.706
Your Current Organism:
Clostridium novyi
NCBI taxonomy Id: 386415
Other names: C. novyi NT, Clostridium novyi NT, Clostridium novyi str. NT, Clostridium novyi strain NT, Clostridium novyi-NT
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.