STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMAN1Protein ERGIC-53. (460 aa)    
Predicted Functional Partners:
MCFD2
Multiple coagulation factor deficiency protein 2 isoform X1.
   
 0.997
SEC22B
Vesicle-trafficking protein SEC22b; Belongs to the synaptobrevin family.
   
 0.833
GOSR2
Golgi SNAP receptor complex member 2 isoform X1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
     
 0.822
SEC13
Protein SEC13 homolog; Belongs to the WD repeat SEC13 family.
   
 
 0.801
SEC23B
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
   
 
 0.782
SEC23A
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
   
 
 0.782
SEC24C
Protein transport protein Sec24C isoform X1.
   
 
 0.779
PREB
Prolactin regulatory element-binding protein.
   
 0.774
STX5
Syntaxin-5; Belongs to the syntaxin family.
    
 0.769
TMED10
Transmembrane emp24 domain-containing protein 10; Belongs to the EMP24/GP25L family.
   
 0.758
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.