STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MC3RMelanocortin receptor 3. (326 aa)    
Predicted Functional Partners:
POMC
Pro-opiomelanocortin.
    
 0.985
MRAP2
Melanocortin-2 receptor accessory protein 2 isoform X1.
    
 
 0.712
MRAP
Melanocortin-2 receptor accessory protein.
    
 
 0.712
AGRP
Agouti-related protein.
    
 
 0.686
GHRL
Appetite-regulating hormone isoform X1.
    
 0.589
NPY
Pro-neuropeptide Y.
    
 0.567
GHSR
Growth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.549
OPN3
Opsin-3; Belongs to the G-protein coupled receptor 1 family.
      
 0.548
CTSZ
Cathepsin Z; Belongs to the peptidase C1 family.
     
 0.480
LEP
Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.
      
 0.472
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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