STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCEH1Neutral cholesterol ester hydrolase 1 isoform X1. (408 aa)    
Predicted Functional Partners:
BDKRB1
B1 bradykinin receptor.
    
 0.767
C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial.
    
 0.605
MGLL
Monoglyceride lipase isoform X1.
     
 0.566
NDUFS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family.
    
 
 0.507
KYNU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.
  
 
 0.503
F2
Prothrombin isoform X1; Belongs to the peptidase S1 family.
   
 0.476
TDO2
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
  
 
 0.473
LOC102381524
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
   
 0.467
HGFAC
Hepatocyte growth factor activator.
   
 0.464
LOC102374591
Cytochrome c1, heme protein, mitochondrial.
    
 0.461
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.