STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNAH8Dynein heavy chain 8, axonemal. (4686 aa)    
Predicted Functional Partners:
PAFAH1B1
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
   
 0.752
DCTN2
Dynactin subunit 2.
    
 0.687
DNAI1
Dynein intermediate chain 1, axonemal.
  
 0.672
DCTN1
Dynactin subunit 1 isoform X1.
   
 0.635
LOC112548499
Dynactin subunit 1-like.
   
 0.635
DYNC1I2
Cytoplasmic dynein 1 intermediate chain 2 isoform X1.
   
 0.619
DYNC1I1
Cytoplasmic dynein 1 intermediate chain 1 isoform X1.
   
 0.619
DYNLL1
Dynein light chain.
    
 0.610
DYNLL2
Dynein light chain.
    
 0.610
DYNC2LI1
Cytoplasmic dynein 2 light intermediate chain 1 isoform X1.
    
 0.590
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.