LEPR protein (Alligator sinensis) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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Score

LEPR

Leptin receptor isoform X1. (1156 aa)

Predicted Functional Partners:

LEP

0.983

JAK2

0.977

SOCS3

0.966

JAK3

0.782

WARS2

0.693

JAK1

0.657

TYK2

0.657

STAT3

0.616

POMC

0.567

GPAT4

0.559

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GPAT4	LEPR	A0A1U7RS67	A0A3Q0H8E2	Glycerol-3-phosphate acyltransferase 4.	Leptin receptor isoform X1.	0.559
JAK1	JAK2	A0A1U7RXD8	A0A3Q0GV11	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.961
JAK1	JAK3	A0A1U7RXD8	A0A3Q0FYA4	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.636
JAK1	LEPR	A0A1U7RXD8	A0A3Q0H8E2	Tyrosine-protein kinase.	Leptin receptor isoform X1.	0.657
JAK1	SOCS3	A0A1U7RXD8	A0A3Q0FPA5	Tyrosine-protein kinase.	Suppressor of cytokine signaling 3.	0.984
JAK1	STAT3	A0A1U7RXD8	A0A3Q0GY41	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.955
JAK1	TYK2	A0A1U7RXD8	A0A1U8D4W6	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.930
JAK2	JAK1	A0A3Q0GV11	A0A1U7RXD8	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.961
JAK2	LEP	A0A3Q0GV11	A0A1U8DFZ0	Tyrosine-protein kinase.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	0.442
JAK2	LEPR	A0A3Q0GV11	A0A3Q0H8E2	Tyrosine-protein kinase.	Leptin receptor isoform X1.	0.977
JAK2	SOCS3	A0A3Q0GV11	A0A3Q0FPA5	Tyrosine-protein kinase.	Suppressor of cytokine signaling 3.	0.988
JAK2	STAT3	A0A3Q0GV11	A0A3Q0GY41	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.992
JAK2	TYK2	A0A3Q0GV11	A0A1U8D4W6	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.630
JAK3	JAK1	A0A3Q0FYA4	A0A1U7RXD8	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.636
JAK3	LEP	A0A3Q0FYA4	A0A1U8DFZ0	Tyrosine-protein kinase.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	0.442
JAK3	LEPR	A0A3Q0FYA4	A0A3Q0H8E2	Tyrosine-protein kinase.	Leptin receptor isoform X1.	0.782
JAK3	SOCS3	A0A3Q0FYA4	A0A3Q0FPA5	Tyrosine-protein kinase.	Suppressor of cytokine signaling 3.	0.862
JAK3	STAT3	A0A3Q0FYA4	A0A3Q0GY41	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.953
JAK3	TYK2	A0A3Q0FYA4	A0A1U8D4W6	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.631
LEP	JAK2	A0A1U8DFZ0	A0A3Q0GV11	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	Tyrosine-protein kinase.	0.442