STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A2ML1Alpha-2-macroglobulin-like protein 1 isoform X1. (1492 aa)    
Predicted Functional Partners:
CBX8
Chromobox protein homolog 8.
    
 0.602
RNF2
LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RING2.
    
 0.504
RING1
E3 ubiquitin-protein ligase RING1.
    
 0.504
CBX4
E3 SUMO-protein ligase CBX4.
    
 0.500
BMI1
Polycomb complex protein BMI-1.
    
 0.499
PCGF2
Polycomb group RING finger protein 2 isoform X1.
    
 0.499
CBX2
Chromobox protein homolog 2.
    
 0.496
SCML2
Sex comb on midleg-like protein 2 isoform X1.
    
 0.490
SCMH1
Polycomb protein SCMH1 isoform X1.
    
 0.490
ASB16
Ankyrin repeat and SOCS box protein 16.
     
 0.467
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.