STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECs4900Biotin--protein ligase; Similar to BIRA_ECOLI gi|1790408 percent identity 99 in 321 aa (Conserved in E.coli K-12). (321 aa)    
Predicted Functional Partners:
ECs0853
Biotin synthetase; Similar to BIOB_ECOLI gi|1786992 percent identity 99 in 346 aa (Conserved in E.coli K-12).
  
 
 0.969
ECs4127
acetylCoA carboxylase BCCP subunit; Similar to ACCB_ECOLI gi|1789653 percent identity 100 in 156 aa (Conserved in E.coli K-12).
 
 
 
 0.961
ECs4899
UDP-N-acetylenolpyruvoylglucosamine reductase; Similar to MURB_ECOLI gi|1790407 percent identity 98 in 342 aa (Conserved in E.coli K-12).
  
  
 0.957
ECs3425
Putative deaminase; Similar to YFHC_ECOLI gi|1788911 percent identity 99 in 178 aa (Conserved in E.coli K-12).
 
    0.909
ECs4436
Biotin sulfoxide reductase; Similar to BISC_ECOLI gi|1789973 percent identity 98 in 739 aa (Conserved in E.coli K-12).
     
  0.900
ECs2516
Hypothetical protein; Similar to YEAZ_ECOLI gi|1788109 percent identity 99 in 231 aa (Conserved in E.coli K-12).
 
    0.896
ECs4128
Acetyl CoA carboxylase biotin carboxylase subunit; Similar to ACCC_ECOLI gi|1789654 percent identity 99 in 449 aa (Conserved in E.coli K-12).
 
 0.884
ECs0467
Bifunctional pyrimidine deaminase/reductase in pathway of riboflavin synthesis; Similar to RIBD_ECOLI gi|1786616 percent identity 97 in 367 aa (Conserved in E.coli K-12).
  
  
 0.880
ECs0789
Molybdate uptake regulatory protein; Similar to MODE_ECOLI gi|1786976 percent identity 100 in 262 aa (Conserved in E.coli K-12).
      
 0.875
ECs1834
N-(5-phosphoribosyl)anthranilate isomerase/indole-3-glycerolphosphate synthetase; Similar to TRPC_ECOLI gi|1787516 percent identity 97 in 453 aa (Conserved in E.coli K-12).
  
  
 0.868
Your Current Organism:
Escherichia coli O157H7 Sakai
NCBI taxonomy Id: 386585
Other names: E. coli O157:H7 str. Sakai, Escherichia coli O157:H7 str. Sakai, Escherichia coli O157:H7 strain Sakai
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.