node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ORW65613.1 | ORW70595.1 | AWC24_18640 | AWC24_03650 | ATP-dependent DNA helicase RuvB; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.796 |
ORW65613.1 | recB | AWC24_18640 | AWC24_12590 | ATP-dependent DNA helicase RuvB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exodeoxyribonuclease V subunit beta; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and rep [...] | 0.491 |
ORW65613.1 | recG | AWC24_18640 | AWC24_17210 | ATP-dependent DNA helicase RuvB; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.737 |
ORW65613.1 | ruvA | AWC24_18640 | AWC24_18635 | ATP-dependent DNA helicase RuvB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.999 |
ORW65613.1 | ruvC | AWC24_18640 | AWC24_18630 | ATP-dependent DNA helicase RuvB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.999 |
ORW65613.1 | uvrA | AWC24_18640 | AWC24_03135 | ATP-dependent DNA helicase RuvB; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC-ATPase UvrA; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.947 |
ORW65613.1 | uvrB | AWC24_18640 | AWC24_03105 | ATP-dependent DNA helicase RuvB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.931 |
ORW65613.1 | uvrC | AWC24_18640 | AWC24_19100 | ATP-dependent DNA helicase RuvB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.929 |
ORW70595.1 | ORW65613.1 | AWC24_03650 | AWC24_18640 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RuvB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.796 |
ORW70595.1 | ORW70599.1 | AWC24_03650 | AWC24_03670 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.995 |
ORW70595.1 | ORW70600.1 | AWC24_03650 | AWC24_03675 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
ORW70595.1 | recB | AWC24_03650 | AWC24_12590 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exodeoxyribonuclease V subunit beta; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and rep [...] | 0.845 |
ORW70595.1 | recG | AWC24_03650 | AWC24_17210 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.954 |
ORW70595.1 | ruvA | AWC24_03650 | AWC24_18635 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.952 |
ORW70595.1 | uvrA | AWC24_03650 | AWC24_03135 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC-ATPase UvrA; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.716 |
ORW70595.1 | uvrB | AWC24_03650 | AWC24_03105 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.829 |
ORW70595.1 | uvrC | AWC24_03650 | AWC24_19100 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.589 |
ORW70599.1 | ORW70595.1 | AWC24_03670 | AWC24_03650 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.995 |
ORW70599.1 | ORW70600.1 | AWC24_03670 | AWC24_03675 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
ORW70599.1 | recB | AWC24_03670 | AWC24_12590 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exodeoxyribonuclease V subunit beta; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and rep [...] | 0.828 |