STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OFLC_LOCUS79GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. (337 aa)    
Predicted Functional Partners:
OFLC_LOCUS3055
RTR1-type domain-containing protein.
    
 
 0.979
OFLC_LOCUS4493
GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.
    
 
 0.969
OFLC_LOCUS7975
GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.
    
 
0.969
OFLC_LOCUS5262
Uncharacterized protein.
   
 
 0.965
OFLC_LOCUS3879
Uncharacterized protein.
   
 
 0.955
OFLC_LOCUS5527
zf-C3Hc3H domain-containing protein.
   
 
 0.954
OFLC_LOCUS7413
Uncharacterized protein.
   
 
 0.954
A0A183I6B3
Uncharacterized protein.
   
 
 0.954
OFLC_LOCUS2988
Uncharacterized protein.
   
 
 0.952
OFLC_LOCUS7037
RPOLD domain-containing protein.
   
 
 0.952
Your Current Organism:
Onchocerca flexuosa
NCBI taxonomy Id: 387005
Other names: O. flexuosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.