STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OFLC_LOCUS2748GXGXG domain-containing protein. (114 aa)    
Predicted Functional Partners:
OFLC_LOCUS7016
Uncharacterized protein.
  
 0.998
OFLC_LOCUS7438
ELFV_dehydrog_N domain-containing protein.
  
 0.926
A0A183HRE3
ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.926
A0A183HSH9
ELFV_dehydrog_N domain-containing protein.
  
 0.926
A0A183I210
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.926
A0A183I0A8
Asparagine synthetase domain-containing protein.
    
 0.913
A0A183I2V9
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
    
 0.913
A0A183I0F6
Uncharacterized protein.
  
 
 0.908
X798_03999
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 
 0.849
A0A183I0F2
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
   
 
 0.847
Your Current Organism:
Onchocerca flexuosa
NCBI taxonomy Id: 387005
Other names: O. flexuosa
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.