A0A183I4T8 protein (Onchocerca flexuosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A183I4T8

Lon protease homolog; Belongs to the peptidase S16 family. (659 aa)

Predicted Functional Partners:

A0A183I7H4

0.890

A0A183I564

0.872

A0A183HUK8

0.852

A0A183I6P1

0.852

OFLC_LOCUS3871

0.741

A0A183HCM5

0.741

OFLC_LOCUS6038

0.741

OFLC_LOCUS3991

0.735

A0A183HYK0

0.735

OFLC_LOCUS2064

0.730

Your Current Organism:

Onchocerca flexuosa

NCBI taxonomy Id: 387005
Other names: O. flexuosa

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A183HCM5	A0A183HUK8	A0A183HCM5	A0A183HUK8	Uncharacterized protein.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.600
A0A183HCM5	A0A183I4T8	A0A183HCM5	A0A183I4T8	Uncharacterized protein.	Lon protease homolog; Belongs to the peptidase S16 family.	0.741
A0A183HCM5	A0A183I564	A0A183HCM5	A0A183I564	Uncharacterized protein.	Uncharacterized protein.	0.997
A0A183HCM5	A0A183I6P1	A0A183HCM5	A0A183I6P1	Uncharacterized protein.	Uncharacterized protein.	0.600
A0A183HCM5	OFLC_LOCUS2064	A0A183HCM5	A0A183H3K4	Uncharacterized protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.596
A0A183HCM5	OFLC_LOCUS3991	A0A183HCM5	A0A183H929	Uncharacterized protein.	Enolase_C domain-containing protein.	0.530
A0A183HUK8	A0A183HCM5	A0A183HUK8	A0A183HCM5	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	Uncharacterized protein.	0.600
A0A183HUK8	A0A183I4T8	A0A183HUK8	A0A183I4T8	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	Lon protease homolog; Belongs to the peptidase S16 family.	0.852
A0A183HUK8	A0A183I564	A0A183HUK8	A0A183I564	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	Uncharacterized protein.	0.885
A0A183HUK8	A0A183I6P1	A0A183HUK8	A0A183I6P1	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	Uncharacterized protein.	0.512
A0A183HUK8	OFLC_LOCUS2064	A0A183HUK8	A0A183H3K4	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.491
A0A183HUK8	OFLC_LOCUS3871	A0A183HUK8	A0A183H8Q9	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	AAA domain-containing protein.	0.600
A0A183HUK8	OFLC_LOCUS3991	A0A183HUK8	A0A183H929	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	Enolase_C domain-containing protein.	0.465
A0A183HUK8	OFLC_LOCUS6038	A0A183HUK8	A0A183HEX6	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	Uncharacterized protein.	0.600
A0A183HYK0	A0A183I4T8	A0A183HYK0	A0A183I4T8	RING-type domain-containing protein.	Lon protease homolog; Belongs to the peptidase S16 family.	0.735
A0A183HYK0	A0A183I7H4	A0A183HYK0	A0A183I7H4	RING-type domain-containing protein.	TPR_REGION domain-containing protein.	0.998
A0A183I4T8	A0A183HCM5	A0A183I4T8	A0A183HCM5	Lon protease homolog; Belongs to the peptidase S16 family.	Uncharacterized protein.	0.741
A0A183I4T8	A0A183HUK8	A0A183I4T8	A0A183HUK8	Lon protease homolog; Belongs to the peptidase S16 family.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.852
A0A183I4T8	A0A183HYK0	A0A183I4T8	A0A183HYK0	Lon protease homolog; Belongs to the peptidase S16 family.	RING-type domain-containing protein.	0.735
A0A183I4T8	A0A183I564	A0A183I4T8	A0A183I564	Lon protease homolog; Belongs to the peptidase S16 family.	Uncharacterized protein.	0.872