STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A183I594Uncharacterized protein. (271 aa)    
Predicted Functional Partners:
OFLC_LOCUS670
TAFII55 protein region.
    
 
 0.906
OFLC_LOCUS132
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.829
OFLC_LOCUS2423
Uncharacterized protein.
    
 
 0.829
A0A183I8N0
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.829
OFLC_LOCUS4524
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 
 0.771
A0A183I0C6
Histone H2A; Belongs to the histone H2A family.
    
 
 0.767
OFLC_LOCUS20
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 
 0.748
OFLC_LOCUS7048
Histone H3; Belongs to the histone H3 family.
    
 
 0.739
A0A183HZK0
Histone domain-containing protein.
    
 
 0.739
A0A183I2P4
Histone domain-containing protein.
    
 
 0.739
Your Current Organism:
Onchocerca flexuosa
NCBI taxonomy Id: 387005
Other names: O. flexuosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.