| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NIS_0815 | NIS_1140 | NIS_0815 | NIS_1140 | Aspartate aminotransferase. | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | 0.836 |
| NIS_0815 | NIS_1441 | NIS_0815 | NIS_1441 | Aspartate aminotransferase. | Asparagine synthase, glutamine-hydrolyzing. | 0.906 |
| NIS_0815 | NIS_1648 | NIS_0815 | NIS_1648 | Aspartate aminotransferase. | Conserved hypothetical protein. | 0.906 |
| NIS_0815 | argG | NIS_0815 | NIS_0998 | Aspartate aminotransferase. | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.920 |
| NIS_0815 | purA | NIS_0815 | NIS_1625 | Aspartate aminotransferase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.905 |
| NIS_1137 | NIS_1140 | NIS_1137 | NIS_1140 | Dihydropteroate synthase. | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | 0.823 |
| NIS_1137 | rppH | NIS_1137 | NIS_1141 | Dihydropteroate synthase. | (di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.824 |
| NIS_1140 | NIS_0815 | NIS_1140 | NIS_0815 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Aspartate aminotransferase. | 0.836 |
| NIS_1140 | NIS_1137 | NIS_1140 | NIS_1137 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Dihydropteroate synthase. | 0.823 |
| NIS_1140 | NIS_1441 | NIS_1140 | NIS_1441 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Asparagine synthase, glutamine-hydrolyzing. | 0.844 |
| NIS_1140 | NIS_1553 | NIS_1140 | NIS_1553 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Homoserine dehydrogenase. | 0.956 |
| NIS_1140 | NIS_1648 | NIS_1140 | NIS_1648 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Conserved hypothetical protein. | 0.844 |
| NIS_1140 | argG | NIS_1140 | NIS_0998 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.872 |
| NIS_1140 | asd | NIS_1140 | NIS_0488 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.985 |
| NIS_1140 | purA | NIS_1140 | NIS_1625 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.819 |
| NIS_1140 | rppH | NIS_1140 | NIS_1141 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | (di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.818 |
| NIS_1140 | thrC | NIS_1140 | NIS_1040 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Threonine synthase. | 0.839 |
| NIS_1441 | NIS_0815 | NIS_1441 | NIS_0815 | Asparagine synthase, glutamine-hydrolyzing. | Aspartate aminotransferase. | 0.906 |
| NIS_1441 | NIS_1140 | NIS_1441 | NIS_1140 | Asparagine synthase, glutamine-hydrolyzing. | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | 0.844 |
| NIS_1441 | NIS_1648 | NIS_1441 | NIS_1648 | Asparagine synthase, glutamine-hydrolyzing. | Conserved hypothetical protein. | 0.924 |
