| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NIS_1140 | NIS_1553 | NIS_1140 | NIS_1553 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Homoserine dehydrogenase. | 0.956 |
| NIS_1140 | NIS_1554 | NIS_1140 | NIS_1554 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Aminotransferase, class I and II. | 0.590 |
| NIS_1140 | asd | NIS_1140 | NIS_0488 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.985 |
| NIS_1140 | dapA | NIS_1140 | NIS_0699 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.656 |
| NIS_1140 | metH | NIS_1140 | NIS_0549 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.569 |
| NIS_1140 | metXA | NIS_1140 | NIS_1276 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.789 |
| NIS_1140 | thrB | NIS_1140 | NIS_0420 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.782 |
| NIS_1140 | thrC | NIS_1140 | NIS_1040 | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | Threonine synthase. | 0.839 |
| NIS_1553 | NIS_1140 | NIS_1553 | NIS_1140 | Homoserine dehydrogenase. | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | 0.956 |
| NIS_1553 | NIS_1554 | NIS_1553 | NIS_1554 | Homoserine dehydrogenase. | Aminotransferase, class I and II. | 0.852 |
| NIS_1553 | asd | NIS_1553 | NIS_0488 | Homoserine dehydrogenase. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.977 |
| NIS_1553 | dapA | NIS_1553 | NIS_0699 | Homoserine dehydrogenase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.949 |
| NIS_1553 | ilvE | NIS_1553 | NIS_1542 | Homoserine dehydrogenase. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.861 |
| NIS_1553 | metE | NIS_1553 | NIS_0886 | Homoserine dehydrogenase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.875 |
| NIS_1553 | metH | NIS_1553 | NIS_0549 | Homoserine dehydrogenase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.932 |
| NIS_1553 | metXA | NIS_1553 | NIS_1276 | Homoserine dehydrogenase. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.954 |
| NIS_1553 | thrB | NIS_1553 | NIS_0420 | Homoserine dehydrogenase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.995 |
| NIS_1553 | thrC | NIS_1553 | NIS_1040 | Homoserine dehydrogenase. | Threonine synthase. | 0.974 |
| NIS_1554 | NIS_1140 | NIS_1554 | NIS_1140 | Aminotransferase, class I and II. | Monofunctional class in bifunctional enzyme ThrA/MetL, aspartokinase I/II EC 2.7.2.4/homeserine dehydrogenase I EC 1.1.1.3; Belongs to the aspartokinase family. | 0.590 |
| NIS_1554 | NIS_1553 | NIS_1554 | NIS_1553 | Aminotransferase, class I and II. | Homoserine dehydrogenase. | 0.852 |
