node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SUN_0137 | SUN_0138 | SUN_0137 | SUN_0138 | Conserved hypothetical protein. | Hypothetical protein. | 0.610 |
SUN_0137 | SUN_0140 | SUN_0137 | SUN_0140 | Conserved hypothetical protein. | Conserved hypothetical protein; Similar to signal transduction response regulator (EAL family protein). | 0.433 |
SUN_0137 | gyrB | SUN_0137 | SUN_0141 | Conserved hypothetical protein. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.433 |
SUN_0137 | queF | SUN_0137 | SUN_0139 | Conserved hypothetical protein. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.437 |
SUN_0138 | SUN_0137 | SUN_0138 | SUN_0137 | Hypothetical protein. | Conserved hypothetical protein. | 0.610 |
SUN_0138 | SUN_0140 | SUN_0138 | SUN_0140 | Hypothetical protein. | Conserved hypothetical protein; Similar to signal transduction response regulator (EAL family protein). | 0.535 |
SUN_0138 | gyrB | SUN_0138 | SUN_0141 | Hypothetical protein. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.595 |
SUN_0138 | queF | SUN_0138 | SUN_0139 | Hypothetical protein. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.539 |
SUN_0140 | SUN_0137 | SUN_0140 | SUN_0137 | Conserved hypothetical protein; Similar to signal transduction response regulator (EAL family protein). | Conserved hypothetical protein. | 0.433 |
SUN_0140 | SUN_0138 | SUN_0140 | SUN_0138 | Conserved hypothetical protein; Similar to signal transduction response regulator (EAL family protein). | Hypothetical protein. | 0.535 |
SUN_0140 | gyrB | SUN_0140 | SUN_0141 | Conserved hypothetical protein; Similar to signal transduction response regulator (EAL family protein). | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.800 |
SUN_0140 | queF | SUN_0140 | SUN_0139 | Conserved hypothetical protein; Similar to signal transduction response regulator (EAL family protein). | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.795 |
gyrB | SUN_0137 | SUN_0141 | SUN_0137 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Conserved hypothetical protein. | 0.433 |
gyrB | SUN_0138 | SUN_0141 | SUN_0138 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Hypothetical protein. | 0.595 |
gyrB | SUN_0140 | SUN_0141 | SUN_0140 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Conserved hypothetical protein; Similar to signal transduction response regulator (EAL family protein). | 0.800 |
gyrB | queF | SUN_0141 | SUN_0139 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.795 |
queF | SUN_0137 | SUN_0139 | SUN_0137 | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | Conserved hypothetical protein. | 0.437 |
queF | SUN_0138 | SUN_0139 | SUN_0138 | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | Hypothetical protein. | 0.539 |
queF | SUN_0140 | SUN_0139 | SUN_0140 | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | Conserved hypothetical protein; Similar to signal transduction response regulator (EAL family protein). | 0.795 |
queF | gyrB | SUN_0139 | SUN_0141 | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.795 |